pentobarbital will minimize the extent or outcome of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will decrease the extent or effect of meloxicam by affecting hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Unfamiliar.
pentobarbital will decrease the extent or effect of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lower the extent or impact of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Watch Closely (one)pentobarbital will reduce the level or impact of osilodrostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or outcome of temsirolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Contraindicated (one)pentobarbital will minimize the extent or influence of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers can result in lessened serum concentrations and loss of antimalarial efficacy
lasmiditan, pentobarbital. Possibly increases effects of another by sedation. Use Warning/Observe. Coadministration of lasmiditan as well as other CNS depressant drugs, including Liquor haven't been evaluated in clinical reports. Lasmiditan may possibly induce sedation, and also other cognitive and/or neuropsychiatric adverse reactions.
pentobarbital will decrease the level or effect of eltrombopag by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.
Contraindicated. The therapeutic effect of elbasvir/grazoprevir could be lessened if coadministered with potent CYP3A inducers which is hence check here contraindicated.
pentobarbital will minimize the level or outcome of cobimetinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Prevent coadministration. Robust or average CYP3A inducers may minimize cobimetinib systemic exposure by >80% and cut down its efficacy.
pentobarbital will decrease the extent or effect of fludrocortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the level or impact of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Outcome of coadministering a powerful CYP3A4 inducer with fedratinib has not been studied.
If inducer is discontinued, consider oliceridine dosage reduction and watch for indications of respiratory melancholy.